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AB2 Bio gets $30M from Nippon Shinyaku for U.S. rights to Tadekinig alfa treating rare hyperinflammatory syndrome

Company Fundamentals
30 Jul 2026
Na
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Bullish
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AB2 Bio received $30 million from Nippon Shinyaku, which exercised its exclusive U.S. commercialization option for Tadekinig alfa, a treatment for Primary Monogenic IL-18-Driven Hyperinflammatory Syndrome, a rare pediatric disease with no FDA-approved therapies. AB2 Bio retains global rights outside the U.S. and for other indications, with potential milestone and royalty payments up to $600 million. The companies aim to accelerate U.S. patient access while AB2 Bio leads regulatory filings. This deal marks a key step toward addressing a critical unmet medical need in ultra-rare inflammatory diseases.

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